Decision support systems (DSS) are transforming healthcare by enabling personalized medicine, which tailors treatment plans and clinical decisions to individual patients based on their unique characteristics, including genomic, clinical, and environmental
data. This special collection will focus on developments in DSS for personalized medicine, emphasizing their design, implementation, and clinical applications.

Submissions should address challenges and solutions in creating adaptable, interpretable, and efficient DSS capable of integrating diverse data types. This collection aims to bridge the gap between theoretical advances and practical implementations, showcasing the role of DSS in enhancing clinical decision-making, patient outcomes, and healthcare efficiency.

We invite submissions on the following topics, but not limited to:

  • Personalized treatment pathways using DSS
  • Integration of DSS with genomic, proteomic, and pharmacogenomic data
  • Real-time clinical decision-making systems for individual patient care
  • Machine Learning and Artificial Intelligence in Decision Support Systems
  • Explainable Artificial Intelligence (XAI) for Interpretable Clinical Decision-Making
  • Wearables and Internet of Things (IoT) Data into Decision Support Systems
  • Interoperability Challenges in the Integration of Decision Support Systems
  • DSS for rare disease diagnosis and management
  • Case studies on successful DSS implementations in personalized medicine
  • Ethical and regulatory considerations in personalized DSS development
  • Data Privacy and Security in Decision Support Systems

Submissions

This special issue will consist of papers from two sources:

  1. The best submissions from an open call for papers.
  2. Invited submissions that are substantial revisions of selected papers accepted at the 38th IEEE International Symposium on Computer-Based Medical Systems (https://2025.cbms-conference.org). The submitted manuscripts from CBMS 2025 are required to have more than 50% new and original technical or scientific content, distinct from the published conference paper. The authors must submit a letter detailing the differences between the conference paper and the version submitted to this collection.

Guest Editors

  • Rosa Sicilia, Università Campus Bio-Medico di Roma, Italy
  • Lucía Prieto Santamaría, Universidad Politécnica de Madrid, Spain
  • TBC

Tentative dates

  • TBC

Contact

For more information, contact the lead guest editor at r[dot] sicilia [at] unicampus[dot] it.